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Pediatr Infect Dis J ; 40(12): e472-e474, 2021 12 01.
Article in English | MEDLINE | ID: covidwho-1447657

ABSTRACT

We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir.


Subject(s)
Agammaglobulinemia/complications , COVID-19/complications , Genetic Diseases, X-Linked/complications , Pneumonia, Viral/virology , SARS-CoV-2 , Adenosine Monophosphate/analogs & derivatives , Adenosine Monophosphate/therapeutic use , Adolescent , Alanine/analogs & derivatives , Alanine/therapeutic use , Antibodies, Viral/blood , Antiviral Agents/therapeutic use , Biomarkers/blood , Bronchoalveolar Lavage Fluid/virology , Fever , Humans , Inflammation/blood , Inflammation/metabolism , Male , Pneumonia, Viral/drug therapy , Pneumonia, Viral/pathology , SARS-CoV-2/isolation & purification , COVID-19 Drug Treatment
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